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BRAIN FOG TEST FULL

Metabolic encephalopathy i.e.Researchers describe brain fog symptoms as “an interaction of physiological, cognitive, and perceptual factors” (1).

Known central nervous system (CNS) disease i.e.

Any abnormality that would prevent electrodes from being placed on the head.

admitted to a floor bed rather than ICU.

able to cooperate with EEG collection and neurometric testing.

sufficient mental capacity to provide informed consent.

Experiencing 'brain fog' symptoms (e.g.confusion, mental slowness, unable to concentrate).

At that visit the Brainscope EEG, mental function tests, and symptom surveys will be repeated.

Follow-up Visit - Participants will return to the clinic for a follow-up visit 45-60 days after discharge from the hospital.

Standard laboratory results including blood counts, chemistry and biomarkers of inflammation obtained as standard of care will be recorded.

Demographics - We will collect demographic information that includes age and sex, along with vital signs, pulse oximetry, and supplemental oxygen requirement, physical exam, neurological exam, lab test results, medications given during hospitalization, and results of any imaging done on the head during hospitalization.

Inventory of COVID Symptoms - Research personnel will collect information about COVID symptoms using standardized PROMIS surveys.

Concussion Symptom Inventory (CSI) - Study personnel will ask questions about symptoms using the CSI which is a standardized tool for evaluating injured patients who have concussion.

BRAIN FOG TEST FULL

Full MoCA assessment - After the Brainscope evaluation patients will be asked questions on the paper-based full MoCA cognitive assessment and the score will be recorded.These are called the Structural Injury classifier (SIC) and Concussion Index (CI) assessments that are computed using FDA cleared algorithms for the likelihood of structural brain injury and the likelihood and severity of brain function impairment. Neurocognitive Assessment (brain function tests) - While the EEG electrodes are still attached, we will perform these assessments that test attention, concentration, reaction time, processing speed, decision making, and executive function.Electroencephalogram (EEG) - We will perform an EEG using a Brainscope device.We will also recruit 5 control patients who are COVID positive but are not experiencing 'brainfog' symptoms. Those patients scoring 25 or less out of 30 will then move forward to the formal written consent process. Screening and Consent - Patients with a diagnosis of COVID-19 will be asked by the research personnel if they are experiencing symptoms of 'brain fog' (confusion, altered memory, headache, trouble concentrating.) Those responding affirmatively will be asked to complete a brief mental status exam (mini MoCA).Condition or diseaseĭiagnostic Test: Brainscope modified EEG and cognitive testing The goal will be to develop an objective measurement of brain function/dysfunction associated with COVID-19 infection which might be employed in future studies of treatments for COVID-19 brain fog and to aid in tracking recovery. A baseline assessment will be performed shortly after hospital presentation and then a second evaluation will be performed 45-60 days post hospital discharge to reassess clinical status, brain electrical biomarkers and neurocognitive performance. We will use the FDA cleared BrainScope medical device in conjunction with standard neurocognitive tests to identify correlations with electrical biomarkers and to potentially identify new, unique patterns of altered brain electrical activity associated with COVID-19 infection. Since the neurologic symptoms of some COVID patients ('brain fog') resemble those of patients with concussion, the aim of this study is to identify EEG and cognitive function changes in COVID patients. Why Should I Register and Submit Results?.